अमेरिकी मरीज को चिकित्सा मील के पत्थर में संशोधित सुअर किडनी प्रत्यारोपण प्राप्त हुआ

US patient receives modified pig kidney transplant in medical milestone

Surgeons at a Massachusetts hospital have achieved a significant medical breakthrough by transplanting a genetically modified pig kidney into a human recipient, offering hope to thousands grappling with kidney failure. The four-hour surgery, conducted at the Massachusetts General Transplant Center in Boston, utilized a genetically edited pig kidney, marking a milestone in organ transplantation.

Following the successful procedure, doctors anticipate the patient's imminent discharge, deeming the transplant a triumph. Dr. Tatsuo Kawa, Director of the Legorreta Center for Clinical Transplant Tolerance at Massachusetts General Hospital, hailed the collective efforts of scientists and physicians spanning decades, expressing optimism that this approach could provide a lifeline to millions worldwide facing kidney failure.

Over five years, researchers at MGH and eGenesis collaborated on genetically modifying the kidney for transplantation. The process involved eliminating harmful pig genes and neutralizing retroviruses in the donor pig to prevent potential infections in humans. Additionally, human genes were introduced into the kidney to enhance compatibility with human recipients.

Richard Slayman, aged 62, received the genetically modified kidney on March 16. Having endured end-stage kidney disease, Slayman underwent dialysis for seven years before a previous kidney transplant in 2018. Complications necessitated his return to dialysis in May 2023. Slayman, viewing the procedure as a beacon of hope for countless others in need of transplants, expressed gratitude for the opportunity to contribute to medical advancements.

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